The predatory life cycle of Myxococcus xanthus

Autor:	James E. Berleman, Ryan Keane
Rok vydání:	2016
Předmět:	0301 basic medicine Genetics Myxococcus xanthus biology Ecology fungi 030106 microbiology Biofilm Model system Social behaviour Spores Fungal biology.organism_classification Microbiology Predation 03 medical and health sciences Multicellular organism Bacterial Proteins bacteria Organism Bacteria
Zdroj:	Microbiology. 162:1-11
ISSN:	1465-2080 1350-0872
Popis:	Myxococcus xanthus is a predatory bacterium and a model system for social behaviour in bacteria. Myx. xanthus forms thin biofilms, where cells work together to colonize new territory, invade prey colonies and lyse prey cells. Prey-cell lysis occurs at close proximity, and utilizes antibiotics such as myxovirescin, hydrolytic enzymes such as the protease MepA and extracellular outer-membrane vesicles that may facilitate delivery. Many questions about the mechanism of prey lysis remain, as well as a complete understanding of the vast hydrolytic and secondary metabolite potential present in the Myx. xanthus genome. However, it is clear that predation presents unique challenges for this bacterium, which are solved, in part, through the social behaviours at the disposal of Myx. xanthus. Here, we discuss the life cycle of Myx. xanthus, and the hypothesis that multicellular behaviour in this organism is critical to, and derives from, the challenges of growth as a bacterial predator.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d37098eda5c5d1e3a8c6c6e0f110d3 https://doi.org/10.1099/mic.0.000208 Zobrazit plný text záznamu