Vagal paraganglioma: The Jefferson experience☆
| Autor: | Maurits Boon, Louis D. Lowry, Joseph P. Atkins, Randy B. Miller |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Vagus Nerve Diseases medicine.medical_specialty medicine.medical_treatment Paraganglioma 03 medical and health sciences 0302 clinical medicine Postoperative Complications Epidemiology medicine Methods Humans Cranial Nerve Neoplasms Embolization Family history 030223 otorhinolaryngology Radiation treatment planning Aged Retrospective Studies medicine.diagnostic_test business.industry Retrospective cohort study Sequela Middle Aged medicine.disease Embolization Therapeutic Surgery Otorhinolaryngology 030220 oncology & carcinogenesis Angiography Cricopharyngeal myotomy Female Radiology business |
| Zdroj: | Otolaryngology - Head and Neck Surgery. 122:482-487 |
| ISSN: | 0194-5998 |
| Popis: | Vagal paraganglioma is a rare tumor of neural crest origin. Although the literature is in agreement with regard to epidemiology, diagnosis, and tumor biology, there is some controversy over treatment modalities for these patients. We performed a nonrandomized retrospective study in a large single-institution series of patients (n = 19) in whom vagal paraganglioma was diagnosed. General statistics included age, male/female ratio, tumor size, and duration of follow-up. Other variables such as signs and symptoms at presentation, family history, multicentricity, metastatic disease, and secretion of catecholamines were included. CT scan, MRI, and angiography were used in combination for diagnostic purposes as well as for treatment planning. Preoperative embolization was performed in 5 of the more recently treated patients. Current issues regarding the use of preoperative embolization and choice of surgical approach were analyzed. In this article the possibility and sequela of vagus nerve-sparing procedures will be presented. Operative complications and postoperative morbidity related to cranial neuropathies will be discussed. The rationale for performing adjunct procedures, including cricopharyngeal myotomy and vocal fold medialization, to facilitate the rehabilitation of patients with postoperative cranial nerve deficits will be given. Our findings and recommendations will be compared with currently accepted treatment protocols in conjunction with a review of the literature. |
| Databáze: | OpenAIRE |
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