Supplementary Methods from Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells

Autor:	Daniel P. Cahill, Hiroaki Wakimoto, Julie J. Miller, Lisa Melamed, Seamus Rafferty, Megha Subramanian, Fumi Higuchi, Kensuke Tateishi, Christine K. Lee, Hiroaki Nagashima
Rok vydání:	2023
DOI:	10.1158/2159-8290.22535455.v1
Popis:	shRNA and Control shRNA Cell Lines, Molecular Analyses, 2-HG Quantitation, Western blot analysis, Immunohistochemistry, TUNEL assay, In Vivo Studies
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c8716f95ed0c3b990e58f050aa749e https://doi.org/10.1158/2159-8290.22535455.v1 Zobrazit plný text záznamu