Treatment of venous ulcers with growth factors: systematic review and meta-analysis
| Autor: | Beatriz Guitton Renaud Baptista de Oliveira, Isabelle Andrade Silveira, Magali Rezende de Carvalho |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
lcsh:RT1-120
Wound Healing lcsh:Nursing Cuidados de Enfermagem Healing Úlcera Varicosa Peptídeos e Proteínas de Sinalização Intercelular Evidence-Based Nursing Enfermagem Baseada em Evidências Varicose Ulcer 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Treatment Outcome 030220 oncology & carcinogenesis Humans Intercellular Signaling Peptides and Proteins Nursing Care Cicatrização General Nursing Randomized Controlled Trials as Topic |
| Zdroj: | Revista Brasileira de Enfermagem v.72 n.1 2019 Revista Brasileira de Enfermagem Associação Brasileira de Enfermagem (ABEN) instacron:ABEN Revista Brasileira de Enfermagem, Vol 72, Iss 1, Pp 200-210 |
| Popis: | Objective: To identify evidence about the effects of growth factor application on venous ulcer healing. Method: Systematic review and meta-analysis, including Randomized Clinical Trials. Searches: Ovid MEDLINE, EMBASE, CINAHL, Cochrane CENTRAL, LILACS, Web of Science, Digital Library of Theses and Dissertations; Google Scholar and list of references. Results: 802 participants were recruited from the 10 included studies: 472 in the intervention group (growth factors) and 330 as control. The relative risk for the complete healing outcome was 1.06 [95% CI 0.92-1.22], p = 0.41. Participants who received Platelet-Rich Plasma and Epidermal Growth Factor showed a slight tendency to achieve complete healing, but without statistical relevance (p |
| Databáze: | OpenAIRE |
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