TANNING SALON EXPOSURE SUPPRESSION OF DNA REPAIR CAPACITY AND MITOGEN-INDUCED DNA SYNTHESIS
| Autor: | T. E. Morris, M. E. Smith, L. L. Larcom |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
DNA Repair Ultraviolet Rays DNA repair Lymphocyte Stimulation In Vitro Techniques Biology Lymphocyte Activation medicine.disease_cause Biochemistry chemistry.chemical_compound medicine Humans Phytohemagglutinins Physical and Theoretical Chemistry Carcinogen Genetics DNA synthesis Cancer DNA General Medicine medicine.disease medicine.anatomical_structure chemistry Immunology Carcinogenesis |
| Zdroj: | Photochemistry and Photobiology. 53:511-516 |
| ISSN: | 1751-1097 0031-8655 |
| DOI: | 10.1111/j.1751-1097.1991.tb03663.x |
| Popis: | — Mitogen responsiveness and the capacity to repair genetic damage were measured in lymphocytes collected from young, healthy, adult Caucasians immediately before exposure in commercial tanning salons and again 24 h after exposure. For every individual studied, tanning exposure produced significant inhibition of phytohemagglutinin-induced mitogenesis or of the ability to repair DNA lesions by unscheduled DNA synthesis. The results imply that such exposure could: (1) pose a significant hazard for individuals who are already immunosuppressed (e. g. cancer patients, AIDS patients or carriers of latent HIV) and (2) increase the carcinogenic effects of environmental mutagens. |
| Databáze: | OpenAIRE |
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