Efficacy of collagen shields after extracapsular cataract extraction
| Autor: | E. Ferrari, Paolo Lanzetta, S. Vita, F Soldano, Ugo Menchini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
genetic structures Eye disease Cataract Extraction Betamethasone Fibrin Injections Cornea 03 medical and health sciences 0302 clinical medicine Endophthalmitis Drug Delivery Systems Ophthalmology medicine Humans Netilmicin Adverse effect Inflammation Lenses Intraocular Piperacillin biology Biological Dressings business.industry General Medicine Drug Tolerance medicine.disease eye diseases Surgery Oxygen medicine.anatomical_structure Tolerability 030221 ophthalmology & optometry biology.protein Itching Drug Therapy Combination sense organs Collagen medicine.symptom business Conjunctiva 030217 neurology & neurosurgery medicine.drug |
| Popis: | The efficacy of presoaked porcine collagen shields was compared with subconjunctivally injected corticosteroids and antibiotics in reducing ocular inflammation after ECCE with IOL implantation, and signs of reduced oxygen delivery to the cornea were assessed. Fifty eyes of fifty patients were recruited. At the end of surgery 25 eyes (group 1) received a 24-h shield presoaked with 0.1% betamethasone disodium phosphate and 0.5% netilmycin. The other 25 eyes (group 2) received 1 mg betamethasone disodium phosphate and 250 mg piperacillin as a subconjunctival injection. The eyes were then taped closed. Inflammatory parameters (anterior chamber flare, fibrin, folds of Descemet's membrane, corneal edema) and tolerability of the delivery system (pain, itching) were evaluated 24 h after surgery. None of the patients lost the shield and the collagen devices were well tolerated. Groups 1 and 2 showed no significant differences in the parameters considered. There was, however, transient, slight diffuse superficial corneal edema in 24% of group 1 and 4% of group 2, raising the question of inadequate oxygen transmission through collagen shields under closed lids. The results suggest that collagen shields used with the right solution have no significant adverse effect and may be a less invasive alternative to subconjunctival injection. |
| Databáze: | OpenAIRE |
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