Helicobacter pyloriInfection in Finnish Children and Adolescents A Serologic Cross-Sectional and Follow-up Study
| Autor: | M. Mäki, Jorma Viikari, Merja Ashorn, M. Hällström, Hans K. Åkerblom, A. Miettinen, M. Uhari |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Adolescent Spirillaceae Helicobacter Infections Serology Immunoenzyme Techniques 03 medical and health sciences Age Distribution 0302 clinical medicine Seroepidemiologic Studies Internal medicine Epidemiology Prevalence medicine Humans Seroprevalence Child Finland Helicobacter pylori biology business.industry Incidence Incidence (epidemiology) Gastroenterology biology.organism_classification Antibodies Bacterial 3. Good health Cross-Sectional Studies El Niño Child Preschool Immunoglobulin G 030220 oncology & carcinogenesis Immunology 030211 gastroenterology & hepatology Gastritis medicine.symptom business Follow-Up Studies |
| Zdroj: | Scandinavian Journal of Gastroenterology. 30:876-879 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.3109/00365529509101594 |
| Popis: | The purpose was to examine the epidemiology of Helicobacter pylori infection in Finnish children and adolescents.Blood samples taken from healthy subjects (n = 461) 3-18 years old were studied cross-sectionally for the presence of H. pylori antibodies. Additionally, blood samples drawn in 1980, 1983, 1986, and 1989 from 74 children born in 1977 were tested. Serum IgG-class antibodies to H. pylori were determined by an enzyme immunoassay.In the cross-sectional series the mean antibody levels and the percentage of seropositive children increased with age. The overall seroprevalence was 10.2%. During the follow-up period from 3 to 12 years of age the seropositivity increased from 4.6% to 5.7%. On the basis of the seroconversions between 3 and 12 years of age the annual incidence of H. pylori infection was calculated to be only 0.3%.In children seropositivity for H. pylori of the IgG class is often a sign of an infection acquired in early childhood. It seems likely that the age-dependent increase in the seropositivity reflects cumulation of a chronic infection. |
| Databáze: | OpenAIRE |
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