Behavioral characteristics of autism spectrum disorder in very preterm birth children

Autor: Yi-Ting Hsieh, Chin Chin Wu, Li Wen Chen, Shan Tair Wang, Ching Lin Chu, Yu Chia Kao, Chao Ching Huang, Lan Wan Wang, Chung-Hsin Chiang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Autism Diagnostic Interview-Revised
Pediatrics
medicine.medical_specialty
Population
Very low birth weight
behavioral disciplines and activities
lcsh:RC346-429
Autism Diagnostic Observation Schedule
Cerebral palsy
03 medical and health sciences
0302 clinical medicine
Developmental Neuroscience
Preterm
mental disorders
Humans
Very Preterm Birth
Medicine
Interpersonal Relations
Autism spectrum disorder
Child
education
Molecular Biology
lcsh:Neurology. Diseases of the nervous system
030304 developmental biology
Behavior
0303 health sciences
education.field_of_study
Intelligence quotient
business.industry
Research
Discriminant Analysis
Gestational age
medicine.disease
Psychiatry and Mental health
Logistic Models
Infant
Extremely Premature
Premature Birth
Term Birth
Female
business
030217 neurology & neurosurgery
Developmental Biology
Zdroj: Molecular Autism, Vol 10, Iss 1, Pp 1-9 (2019)
Molecular Autism
ISSN: 2040-2392
DOI: 10.1186/s13229-019-0282-4
Popis: Background Lower gestational age may increase autism spectrum disorder (ASD) vulnerability; however, the incidence of ASD diagnosis through a direct assessment on every very preterm birth child on the population base remains unclear. Moreover, the behavioral characteristics of preterm birth ASD are unknown. Methods Every very preterm birth child (gestational age 37 weeks) ASD children characterized by ADOS and ADI-R were group matched to the preterm birth ASD by age at examination for comparison. ADOS severity scores were calculated by the Mann–Whitney U test and ADI-R by multivariate analysis of variance and canonical discriminant analysis. Results Two hundred forty-six (87%) of the 283 very preterm survivors were followed prospectively to 5 years of age. Nineteen (7.7%) of the 246 children fulfilled the diagnostic criteria of ASD. After excluding 1 patient with cerebral palsy and profound mental disability, 18 preterm ASD children were compared with 44 term birth ASD children. The two ASD groups were comparable for age at examination, gender, and intelligence quotient. The two groups showed comparable ADOS severity scores in social affect deficits, restricted repetitive behaviors, and total score, but had differences in qualitative abnormalities in reciprocal social interaction (Wilks lambda F value = 6.2, P
Databáze: OpenAIRE
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