Circulation Time-Optimized Albumin Nanoplatform for Quantitative Visualization of Lung Metastasis via Targeting of Macrophages

Autor:	Hyewon Chung, Ji Yong Park, Kyuwan Kim, Ran Ji Yoo, Minseok Suh, Gyo Jeong Gu, Jin Sil Kim, Tae Hyeon Choi, Jung Woo Byun, Young Wook Ju, Wonshik Han, Han Suk Ryu, Gehoon Chung, Do Won Hwang, Yujin Kim, Hye-Ryun Kang, Yi Rang Na, Hongyoon Choi, Hyung-Jun Im, Yun-Sang Lee, Seung Hyeok Seok
Rok vydání:	2022
Předmět:	Blood Circulation Time Lung Neoplasms Macrophages General Engineering Humans General Physics and Astronomy General Materials Science Mannose Serum Albumin
Zdroj:	ACS Nano. 16:12262-12275
ISSN:	1936-086X 1936-0851
Popis:	The development of molecular imaging probes to identify key cellular changes within lung metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study, we constructed a macrophage-targeted clickable albumin nanoplatform (CAN) decorated with mannose as the targeting ligand using a click reaction to maintain the intrinsic properties of albumin
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a27b05b051a40838859d99d5a4d002 https://doi.org/10.1021/acsnano.2c03075 Zobrazit plný text záznamu