Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases

Autor:	Steven T. Pals, Helga Gleichmann, Anton G. Rolink, Thadädus Radaszkiewicz, E Gleichmann
Rok vydání:	2014
Předmět:	Pathogenesis surgical procedures operative Graft versus host reactions Immunology Immune regulation Immunological diseases chemical and pharmacologic phenomena Parental strain Biology Mhc antigens Host disease Pathological
Zdroj:	Immunology today. 5(11)
ISSN:	0167-5699
Popis:	Parental strain T lymphocytes injected into adult F, mice respond to allogeneic MHC antigens and so induce the symptoms of systemic graft v. host disease (GVHD). GVHD has two forms, stimulatory and suppressive, and in each there are pathological changes which resemble those seen in a variety of human disorders of immune regulation. In this article Ernst Gleichmann and his colleagues review the pathogenesis of these disorders and their induction by GVH reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a109549c430df850cc3d58faa687b5 https://pubmed.ncbi.nlm.nih.gov/25290757 Zobrazit plný text záznamu