Visually lossless threshold determination for microcalcification detection in wavelet compressed mammograms
| Autor: | L. Varaki, E. Likaki, Lena Costaridou, Christina Kalogeropoulou, G.S. Panayiotakis, Spyros Skiadopoulos, Otilia Kocsis |
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| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Breast Neoplasms Sensitivity and Specificity Severity of Illness Index Cohort Studies Diagnosis Differential Wavelet Pressure Humans Medicine Radiology Nuclear Medicine and imaging Aged Probability Observer Variation Lossless compression Standard test image Receiver operating characteristic business.industry Calcinosis Wavelet transform Pattern recognition General Medicine Middle Aged Radiographic Image Enhancement ROC Curve Compression ratio Female Clinical Competence Microcalcification Artificial intelligence Radiology medicine.symptom business Mammography Data compression |
| Zdroj: | European Radiology. 13:2390-2396 |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-003-1826-7 |
| Popis: | The aim of this study was to determine the visually lossless threshold of a wavelet-based compression algorithm in case of microcalcification cluster detection in mammography. The threshold was determined by means of observer performance using a set of digitized mammograms. In addition, the transfer characteristics of the compression algorithm were assessed by means of image-quality parameters using computer-generated test images. The observer performance study was based on rating performed by four independent radiologists, who reviewed 68 mammograms, from the Digital Database for Screening Mammography (DDSM), at six different compression ratios. Receiver operating characteristics (ROC) analysis was performed on observers' responses and the area under ROC curve (A(z)) was calculated at each compression ratio for each observer. The parameters used for assessment of transfer characteristics of the compression algorithm were input/output response, noise, high-contrast response, and low-contrast-detail response. The computer-generated test image, used for this assessment, mimicked mammographic image characteristics (pixel size, pixel depth, and noise) as well as microcalcification characteristics (size and contrast). The ROC analysis for microcalcification cluster detection indicated a threshold at compression ratio 40:1, as Student's t-test shows statistically significant differences in A(z) values (p0.05) for compression ratios 70:1 and 100:1. Observers' grading of mammogram quality lowers this threshold at 25:1. Low-contrast-detail detectability in the transfer characteristics study indicate a threshold of 35:1, whereas non-perceptibility of image-quality-parameters degradation lowers this threshold to 30:1. The ROC and transfer characteristics analysis provided comparable thresholds, indicating the potential use of the latter in limiting the target range of compression ratios for subsequent observer studies. |
| Databáze: | OpenAIRE |
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