Supplementary Figures and Methods from EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis

Autor: Kornelia Polyak, Jason S. Carroll, Carlos Caldas, Andrew H. Beck, Oscar M. Rueda, Clive S. D'Santos, Andriy Marusyk, Ying Su, Katherine Murphy, Evangelia K. Papachristou, Chandra Sekhar Reddy Chilamakuri, Anne Trinh, Francisco Beca, Laura E. Stevens, Felipe Flores, Bojana Jovanović, Natalie Kingston, Nicholas W. Harper, Ashim Subedee, Guillermo Peluffo
Rok vydání: 2023
DOI: 10.1158/0008-5472.22422632.v1
Popis: Supplementary Figure S1. Transcription factors enriched in TNBC. Supplementary Figure S2. EN1 is a dependency in TNBC cell lines. Supplementary Figure S3. Transcriptional and genomic targets of EN1 in TNBC cells. Supplementary Figure S4. The effect of CTNNB1 expression in TNBC cells. Supplementary Figure S5. Cellular and molecular changes following EN1 expression in MCF7 cells. Supplementary Figure S6. Expression of EN1 in human breast tumors.
Databáze: OpenAIRE