Colonoscopy-controlled intra-individual comparisons to screen relevant neoplasia: faecal immunochemical test vs. guaiac-based faecal occult blood test
| Autor: | R L J van Wanrooij, A. A. Bouman, Johannes Berkhof, J. S. Terhaar sive Droste, Veerle M.H. Coupé, H. A. van Heukelem, Ruud J.L.F. Loffeld, Gerrit A. Meijer, R. W. M. Van Der Hulst, S. Van Der Reijt, Frank A. Oort, L. De Baaij, E. R. Mutsaers, I.C.E. Wesdorp, Cjj Mulder |
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| Přispěvatelé: | Gastroenterology and hepatology, Epidemiology and Data Science, Pathology, CCA - Disease profiling, Clinical chemistry |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Adenoma Colorectal cancer education Population Colonoscopy Sensitivity and Specificity Gastroenterology Feces Young Adult Predictive Value of Tests Internal medicine medicine Humans Mass Screening Pharmacology (medical) Young adult Early Detection of Cancer Aged Aged 80 and over education.field_of_study Hepatology medicine.diagnostic_test business.industry Cancer Middle Aged medicine.disease Intra individual Immunohistochemistry digestive system diseases Occult Blood Predictive value of tests Female Indicators and Reagents Colorectal Neoplasms Guaiac business |
| Zdroj: | Alimentary Pharmacology and Therapeutics, 31(3), 432-439 Oort, F A, Terhaar sive Droste, J S, van der Hulst, R W M, Van Heukelem, H A, Loffeld, R J, Wesdorp, I C E, van Wanrooij, R L J, de Baaij, L R, Mutsaers, E R, van der Reijt, S, Coupe, V M H, Berkhof, J, Bouman, A A, Meijer, G A & Mulder, C J J 2010, ' Colonoscopy-controlled intra-individual comparisons to screen relevant neoplasia: faecal immunochemical test vs. guaiac-based faecal occult blood test ', Alimentary Pharmacology and Therapeutics, vol. 31, no. 3, pp. 432-439 . https://doi.org/10.1111/j.1365-2036.2009.04184.x |
| ISSN: | 1365-2036 0269-2813 |
| DOI: | 10.1111/j.1365-2036.2009.04184.x |
| Popis: | Aliment Pharmacol Ther 31, 432–439 Summary Background Guaiac-based faecal occult blood tests (g-FOBTs) are most commonly used in colorectal cancer (CRC) screening programmes. Faecal immunochemical tests (FITs) are thought to be superior. Aim To compare performance of a g-FOBT and a quantitative FIT for detection of CRCs and advanced adenomas in a colonoscopy-controlled population. Methods We assessed sensitivity and specificity of both FIT (OC-sensor) and g-FOBT (Hemoccult-II) prior to patients’ scheduled colonoscopies. Results Of the 62 invasive cancers detected in 1821 individuals, g-FOBT was positive in 46 and FIT in 54 (74.2% vs. 87.1%, P = 0.02). Among 194 patients with advanced adenomas, g-FOBT was positive in 35 and FIT in 69 (18.0% vs. 35.6%, P |
| Databáze: | OpenAIRE |
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