Thymic epithelial turnours
| Autor: | Theo J. Klinkenberg, Johannes L. G. Blaauwgeers, Wim Timens, Michael Schaapveld, Harry J.M. Groen, Wouter K. de Jong |
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| Přispěvatelé: | Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Groningen Research Institute for Asthma and COPD (GRIAC) |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Thymoma PROGNOSIS diagnosis Population MALIGNANT THYMOMA Gastroenterology survival Age Distribution Internal medicine Epidemiology TRANSTHORACIC NEEDLE-BIOPSY medicine Humans education PREDICTORS RECURRENCE Survival analysis Aged Neoplasm Staging Netherlands Malignant Thymoma education.field_of_study therapy Relative survival business.industry Incidence (epidemiology) Thymus Neoplasms Middle Aged medicine.disease ORGANIZATION HISTOLOGIC CLASSIFICATION Survival Analysis TUMORS Cancer registry Surgery thymic epithelial tumour Oncology population-based study incidence Female business NEOPLASMS |
| Zdroj: | European Journal of Cancer, 44(1), 123-130. ELSEVIER SCI LTD |
| ISSN: | 0959-8049 |
| DOI: | 10.1016/j.ejca.2007.11.004 |
| Popis: | The population-based incidence, diagnostic procedures, therapy and survival of thymic epithelial tumours were determined using the Netherlands National Pathological Archives and the Netherlands Cancer Registry. Excess mortality compared to the Netherlands standard population was estimated by relative survival analysis.Between 1994 and 2003, 537 thymic epithelial tumours were diagnosed. The incidence of all thymic epithelial tumours was 3.2/1,000,000. Diagnosis was obtained by primary resection in 56% of cases. Survival data were available for 232 cases. Not only thymic carcinomas (type C) but also thymomas (types B1-B3) were associated with excess mortality. Cases that underwent resection (78%) had a better survival than non-operated cases (median survival >10 years versus 1.1 years, p Thymic epithelial tumours are rare. Excess mortality was observed in the majority of tumours. Surgery offers the best perspectives, even if the resection is incomplete. (c) 2007 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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