Partial volume correction for improved PET quantification in 18F-NaF imaging of atherosclerotic plaques

Autor: Daniel Heber, Xiang Li, Ivo Rausch, Stephen C. Moore, Klaus P. Schäfers, Thomas Beyer, Jacobo Cal-Gonzalez, Marcus Hacker
Rok vydání: 2017
Předmět:
Zdroj: Journal of Nuclear Cardiology. 25:1742-1756
ISSN: 1532-6551
1071-3581
DOI: 10.1007/s12350-017-0778-2
Popis: Accurate quantification of plaque imaging using 18F-NaF PET requires partial volume correction (PVC). PVC of PET data was implemented by the use of a local projection (LP) method. LP-based PVC was evaluated with an image quality (NEMA) and with a thorax phantom with “plaque-type” lesions of 18-36 mL. The validated PVC method was then applied to a cohort of 17 patients, each with at least one plaque in the carotid or ascending aortic arteries. In total, 51 calcified (HU > 110) and 16 non-calcified plaque lesions (HU
Databáze: OpenAIRE