Partial volume correction for improved PET quantification in 18F-NaF imaging of atherosclerotic plaques
Autor: | Daniel Heber, Xiang Li, Ivo Rausch, Stephen C. Moore, Klaus P. Schäfers, Thomas Beyer, Jacobo Cal-Gonzalez, Marcus Hacker |
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Rok vydání: | 2017 |
Předmět: |
Thorax
medicine.medical_specialty business.industry Partial volume correction 030204 cardiovascular system & hematology Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Radiology Nuclear Medicine and imaging Medicine Plaque imaging Radiology Nuclear Medicine and imaging In patient Radiology Cardiology and Cardiovascular Medicine 18f fluoride business Nuclear medicine Pet quantification Phantom studies |
Zdroj: | Journal of Nuclear Cardiology. 25:1742-1756 |
ISSN: | 1532-6551 1071-3581 |
DOI: | 10.1007/s12350-017-0778-2 |
Popis: | Accurate quantification of plaque imaging using 18F-NaF PET requires partial volume correction (PVC). PVC of PET data was implemented by the use of a local projection (LP) method. LP-based PVC was evaluated with an image quality (NEMA) and with a thorax phantom with “plaque-type” lesions of 18-36 mL. The validated PVC method was then applied to a cohort of 17 patients, each with at least one plaque in the carotid or ascending aortic arteries. In total, 51 calcified (HU > 110) and 16 non-calcified plaque lesions (HU |
Databáze: | OpenAIRE |
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