Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Autor: Victor M. Corman, Florian Kurth, Willi Koch, Leif E. Sander, Christian Drosten, Stefanie Kasper, Tatjana Schwarz, Claudia Conrad, Terry Jones, Daniela Niemeyer, David Hillus, Norbert Suttorp, Pinkus Tober-Lau, Janine Michel, Kai Kappert, Barbara Mühlemann, Rudolf Tauber, Christof von Kalle, Friederike Münn, Irmgard Landgraf, Andreas Nitsche, Harald Bias, Elisa T Helbig, Leon Bergfeld, Lena J Lippert, Piotr Kopankiewicz, Joachim Seybold, Chantip Dang-Heine, Sein Schmidt, Charlotte Thibeault
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Pediatrics
Epidemiology
T-Lymphocytes
Psychological intervention
Infectious and parasitic diseases
RC109-216
Disease
medicine.disease_cause
0302 clinical medicine
Germany
vaccine
antibody
030212 general & internal medicine
Coronavirus
Aged
80 and over
B cell
biology
Vaccination
Dispatch
Berlin
Infectious Diseases
coronavirus disease
Medicine
Antibody
severe acute respiratory syndrome coronavirus 2
Adult
Microbiology (medical)
medicine.medical_specialty
COVID-19 Vaccines
mRNA
030231 tropical medicine
T cell response
respiratory infections
03 medical and health sciences
Elderly persons
Immunity
medicine
Humans
viruses
ddc:610
BNT162 Vaccine
Aged
SARS-CoV-2
business.industry
COVID-19
T cell
immunity
zoonoses
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly
Germany
biology.protein
business
610 Medizin und Gesundheit
Zdroj: Emerg Infect Dis
Emerging Infectious Diseases, Vol 27, Iss 8, Pp 2174-2178 (2021)
Emerging Infectious Diseases
DOI: 10.25646/9434
Popis: We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.
Databáze: OpenAIRE
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