Association between diabetes mellitus and health-related quality of life among patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)
Autor: | Li Chen, Jinwei Wang, Xiaoyan Huang, Fang Wang, Wei Liang, Yan He, Yumei Liao, Luxia Zhang, Minghui Zhao, Zuying Xiong, on behalf of the C-STRIDE study group |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty China Health-related quality of life Population Renal function 030209 endocrinology & metabolism Disease Comorbidity 030204 cardiovascular system & hematology lcsh:Computer applications to medicine. Medical informatics Cohort Studies 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Quality of life Internal medicine Chronic kidney disease Prevalence Medicine Humans Estimated glomerular filtration rate Prospective Studies Stage (cooking) Renal Insufficiency Chronic education Aged education.field_of_study business.industry Research Public Health Environmental and Occupational Health General Medicine Middle Aged medicine.disease Case-Control Studies Quality of Life lcsh:R858-859.7 Female business Kidney disease Cohort study |
Zdroj: | Health and Quality of Life Outcomes Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-8 (2020) |
ISSN: | 1477-7525 |
Popis: | Background The prevalence of diabetes mellitus (DM) among patients with chronic kidney disease (CKD) has been increasing in recent years in China. This study aimed to evaluate the association between DM and health-related quality of life (HRQOL) in patients with CKD. Methods In our study, participants with CKD stage 1 to 4 from 39 centers in China were screened and enrolled. The Kidney Disease Quality of Life (KDQOL™-36) questionnaire was used to assess HRQOL. Participants were divided into a diabetic group and a non-diabetic group. Demographic data, clinical data, and HRQOL scores were compared between the two groups. Multivariable robust regression was used to analyze the factors related to HRQOL in CKD patients. Results A population of 2742 CKD patients was included in this study. CKD patients with DM were older and had lower education level, longer treatment periods and a higher prevalence of cardiovascular disease than CKD patients without DM (P P < 0.05). DM was negatively correlated with the symptoms and problems (regression coefficient for log transformed [175-score] = 0.010) and the SF-12 physical function dimension (regression coefficient = − 2.18) (all P Conclusion HRQOL of diabetic patients with CKD was worse than that of non-diabetic patients with CKD. DM was an independent and negative factor affecting HRQOL in patients with CKD. |
Databáze: | OpenAIRE |
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