Simultaneous Fluorescence Sensing of Cys and GSH from Different Emission Channels
| Autor: | Linfang Wang, Jing Liu, Yawei Shi, Yuan-Qiang Sun, Dan Song, Wei Guo, Yingying Huo, Pei Zhang, Hong-Xing Zhang |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Cyanides
Time Factors Molecular Structure Chemistry Fluorescence sensing General Chemistry Glutathione Carbocyanines Photochemistry Mass spectrometry Biochemistry Fluorescence Catalysis chemistry.chemical_compound Spectrometry Fluorescence Colloid and Surface Chemistry Coumarins COS Cells Chlorocebus aethiops Animals Molecule heterocyclic compounds Excitation Fluorescent Dyes |
| Zdroj: | Journal of the American Chemical Society. 136:574-577 |
| ISSN: | 1520-5126 0002-7863 |
| Popis: | A chlorinated coumarin-hemicyanine dye with three potential reaction sites was exploited as fluorescent probe for biothiols. The Cys-induced substitution-rearrangement-cyclization, Hcy-induced substitution-rearrangement, and GSH-induced substitution-cyclizatioin cascades lead to the corresponding amino-coumarin, amino-coumarin-hemicyanine, thiol-coumarin with distinct photophysical properties, enabling Cys and GSH to be selectively detected from different emission channels at two different excitation wavelengths. |
| Databáze: | OpenAIRE |
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