Effects of Endurance Training on Skeletal Muscle Oxidative Capacities with and without Selenium Supplementation
| Autor: | J.-F. Marini, E Prou, Irène Margaritis, F Tessier, P Marconnet |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Muscle Fibers Skeletal chemistry.chemical_element Physical exercise Biochemistry Electron Transport Complex IV Placebos Inorganic Chemistry Selenium Oxygen Consumption Double-Blind Method Endurance training Internal medicine medicine Humans Vitamin E Aerobic exercise Muscle Skeletal Creatine Kinase chemistry.chemical_classification Analysis of Variance Glutathione Peroxidase Myosin Heavy Chains biology Glutathione peroxidase Skeletal muscle Mitochondria Muscle Succinate Dehydrogenase medicine.anatomical_structure Endocrinology chemistry Fluorescent Antibody Technique Direct Physical Fitness Physical Endurance biology.protein Molecular Medicine Creatine kinase |
| Zdroj: | Journal of Trace Elements in Medicine and Biology. 11:37-43 |
| ISSN: | 0946-672X |
| DOI: | 10.1016/s0946-672x(97)80008-9 |
| Popis: | The purpose of this study was to examine the changes induced by endurance training, with or without selenium (Se) supplementation on: 1) mitochondrial activity of succinate dehydrogenase (SDH) and cytochrome c oxidase (Cyt Ox),2) the myosin heavy chain (MHC) expression in muscle fibers and 3) their association with aerobic performance. Twenty-four male students volunteered to participate in this double blind study: selenium (Sel, N = 12) vs placebo (Pla, N = 12). During a 10-wk endurance training program, the Sel group received a daily Se supplementation containing 180 micrograms of organic selenium (selenomethionine), while the Pla group received a placebo. Before (Pre) and after (Post) the program (3 sessions wk-1) an endurance exercise (Capmax) was performed in order to determine the aerobic endurance capacity assessed by the total oxygen uptake during the running test (VO2tot). All parameters of aerobic performance were increased in both groups, concomitantly to a rise in mitochondrial Cyt Ox activity. Two positive relationships were found: 1) between type I MHC and VO2tot increments (r = 0.65, P < 0.05), 2) between training volumes and VO2tot increments (r = 0.53, P < 0.05; N = 23). The training program produced an 8.2% significant increase in type I MHC (P < 0.05) while type II MHC decrease was not significant (-4.4%). Although they were almost non-existent before the program, muscle fibers which co-expressed type I and II MHC displayed a marked increase afterwards (4.9 +/- 5.7 vs 1.1 +/- 2.1%, P < 0.05). Muscle GSH-Px activity, at rest, did not respond to endurance training or Se supplementation. The results suggest that the neuromuscular system is still in an evolutive state after 10 weeks of endurance training, and that selenium supplementation has no effect on endurance training-induced adaptations. |
| Databáze: | OpenAIRE |
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