Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury
| Autor: | A. V. Deryugina, I. S. Simutis, G. A. Boyarinov, E. S. Filippenko, Ya. V. Galkina, A. V. Shumilova |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Erythrocytes Pyridines Traumatic brain injury Period (gene) Drug Evaluation Preclinical Acute blood loss Hemodynamics Hemorrhage Body weight General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Blood loss Hematologic Agents Internal medicine Brain Injuries Traumatic medicine Animals business.industry 030208 emergency & critical care medicine General Medicine Malondialdehyde medicine.disease Rats Endocrinology 030228 respiratory system chemistry Anesthesia Concomitant Female business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 164:26-29 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-017-3918-4 |
| Popis: | Mexicor treatment (8 mg/kg body weight per day) during the posttraumatic period after concomitant traumatic brain injury and acute blood loss in rats increased electrophoretic mobility and concentration of 2,3-diphosphoglycerate, and reduced malondialdehyde content in erythrocytes. These changes improved hemodynamics and oxygen-transporting function of the blood. The most pronounced effects of Mexicor were observed at the early stages of posttraumatic period. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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