New glucosidated indole-quinazoline alkaloids from mangrove endophytic fungus Aspergillus fumigatus SAl12

Autor:	Shili Guo, Haiming Zhou, Xin Huang, Siyan Peng, Jiayi Li, Bo Ding, Yiwen Tao, Hongbo Huang
Rok vydání:	2023
Předmět:	Organic Chemistry Plant Science Biochemistry Analytical Chemistry
Zdroj:	Natural Product Research. :1-6
ISSN:	1478-6427 1478-6419
DOI:	10.1080/14786419.2023.2209822
Popis:	Two new glucosidated indole-containing quinazoline alkaloids designated fumigatosides G (1) and H (2) were isolated from mangrove-derived fungus Aspergillus fumigatus SAl12, together with the known analogues fumigatoside B (3) and fumiquinazoline J (4). The planar structures of the new compounds were elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configurations were determined by comparison of electronic circular dichroic (ECD) spectra with that of the known compound fumigatoside B and with the calculated ECD spectrum. All these indole-quinazoline compounds were tested for anti-bacterial and cytotoxic activities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655bf27762d3efbdae8707110a673cae https://doi.org/10.1080/14786419.2023.2209822 Zobrazit plný text záznamu