Transperineal TRUS-guided prostate brachytherapy using loose seeds versus RAPIDStrand: A dosimetric analysis
| Autor: | Richard J. Keys, Mary F. Wojcik, Humberto M. Fagundes, Marsha A. Radden, Carol G. Bertelsman, William Cavanagh |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_treatment Brachytherapy Rectum Perineum Prostate cancer Radiation Monitoring Prostate medicine Humans Dosimetry Radiology Nuclear Medicine and imaging Ultrasonography business.industry Urinary retention Prostatic Neoplasms medicine.disease medicine.anatomical_structure Oncology medicine.symptom Nuclear medicine business Prostate brachytherapy |
| Zdroj: | Brachytherapy. 3:136-140 |
| ISSN: | 1538-4721 |
| DOI: | 10.1016/j.brachy.2004.05.006 |
| Popis: | PURPOSE: An analysis of the effect of stranded 125 I and loose (predominantly 103 Pd) sources on dosimetric outcomes of brachytherapy of the prostate. METHODS AND MATERIALS: Between September 1998 and December 2003, 473 patients were treated with brachytherapy for biopsy-proven carcinoma of the prostate. Of these, 337 (71%) procedures were performed using free seeds placed with a Mick applicator. Beginning in April 2002, a program of stranded 125 I sources (RAPIDStrand) was implemented; 136 (29%) patients were treated via this approach. Dosimetric variables were collected, as were events of urinary retention. RESULTS: Mean V100 values for the stranded 125 I approach were greater than those for free seeds (p 0.0005), whether 125 Io r 103 Pd (p 0.005). Use of the strand was the most significant determinant of V100 of all variables examined. The stranded 125 I approach was also associated with higher mean D90 values and lower V150-urethral doses. CONCLUSIONS: Use of stranded 125 I was associated with superior dosimetric outcomes in this |
| Databáze: | OpenAIRE |
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