Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age

Autor: Joshua A. Frankfurt, Roy J. Heyne, Charles R. Rosenfeld, Andrea F. Duncan
Rok vydání: 2011
Předmět:
Zdroj: Pediatric nephrology (Berlin, Germany). 27(12)
ISSN: 1432-198X
Popis: Preterm very-low-birth-weight (PT-VLBW) infants are at risk of an elevated systolic blood pressure (SBP) in infancy and adulthood; however, the pathogenesis remains unclear. Altered renal development or function may be associated with increased SBP, but their contribution in PT-VLBW is unknown. We determined renal function and its relationship to SBP in three groups of PT-VLBW at 1, 2, and 3 years of age, using serum cystatin-C to calculate the estimated glomerular filtration rate (eGFR). Cystatin-C levels decreased from 0.84 ± 0.2 (SD) within the 1-year group to 0.70 ± 0.1 mg/l (±SD; P
Databáze: OpenAIRE