Atypical Mycobacterial Infection in Anophthalmic Sockets With Porous Orbital Implant Exposure
Autor: | Min Joung Lee, Namju Kim, Ho-Kyung Choung, Youn Joo Choi, Eun Kyu Oh, Sang In Khwarg |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Prosthesis-Related Infections 030106 microbiology Mycobacterium Infections Nontuberculous Conjunctival Diseases Eye Enucleation Eye Infections Bacterial 03 medical and health sciences 0302 clinical medicine Risk Factors Orbital Diseases medicine Humans Risk factor Aged Retrospective Studies business.industry Case-control study Retrospective cohort study Nodule (medicine) Eye infection Prosthesis Failure Surgery Ophthalmology Durapatite medicine.anatomical_structure Polyethylene Case-Control Studies Eyelid Diseases 030221 ophthalmology & optometry Female Implant Eyelid medicine.symptom Tomography X-Ray Computed business Porosity Eye Evisceration Orbital Implants |
Zdroj: | American Journal of Ophthalmology. 195:131-142 |
ISSN: | 0002-9394 |
DOI: | 10.1016/j.ajo.2018.07.041 |
Popis: | Purpose To investigate the clinical features and risk factors of atypical mycobacterial infection in anophthalmic sockets with porous orbital implant exposure. Design Case-control study. Methods The medical records of all patients who had undergone surgical correction of porous orbital implant exposure were consecutively reviewed, and the patients were stratified as those with atypical mycobacterial infection (AM infection group) and others (non-AM group). Results Five and 21 patients were included in the AM infection and non-AM groups, respectively. All patients of the AM infection group had a peg or motility coupling post (MCP) and showed implant exposure around it. Following up on implant exposure, 2 patients abruptly presented with severe conjunctival injection and new lesions such as erythematous nodules or eyelid masses. They underwent immediate orbital implant exchange and atypical mycobacterial infection was diagnosed. Three patients who were not suspected of having infection underwent surgery for orbital implant exposure. Results revealed erythematous eyelid nodule or recurrent exposure shortly after surgery and patients were diagnosed with atypical mycobacterial infection. In the non-AM group, 7 (33.3%) patients underwent insertion of a peg or MCP. Statistical analysis showed that the insertion of a peg or MCP was the only risk factor showing a significant difference between the 2 groups. Conclusions The most important underlying risk factor for atypical mycobacterial infection in the anophthalmic socket is thought to be peg- or MCP-related exposure of the porous orbital implant. Surgical removal of the infected orbital implant and long-term antibiotic medication are needed for treatment. |
Databáze: | OpenAIRE |
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