The relationship between steps of 6MWT and COPD severity: a cross-sectional study
| Autor: | Xi He, Hui-zhen Fan, Hua-Peng Yu, Guan-Sheng Zeng, Ze-Kui Fang, Ling-Ling Wu, Li-Chang Chen, Xi-Ping Wu |
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| Rok vydání: | 2019 |
| Předmět: |
Spirometry
Male medicine.medical_specialty Cross-sectional study Health Status Vital Capacity steps Walk Test Walking International Journal of Chronic Obstructive Pulmonary Disease Severity of Illness Index Pulmonary function testing 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Quality of life DLCO Predictive Value of Tests Diffusing capacity Internal medicine Forced Expiratory Volume Oscillometry Surveys and Questionnaires 6MWT medicine Humans COPD 030212 general & internal medicine Lung Aged Original Research Exercise Tolerance medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Prognosis hyperinflation Impulse Oscillometry Cross-Sectional Studies 030228 respiratory system Quality of Life Pulmonary Diffusing Capacity Female business |
| Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease |
| ISSN: | 1178-2005 |
| Popis: | Guan-Sheng Zeng,* Li-Chang Chen,* Hui-Zhen Fan, Ling-Ling Wu, Xi-Ping Wu, Ze-Kui Fang, Xi He, Hua-Peng Yu Department of Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China *These authors contributed equally to this work Background and objective: The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT and other physiologic parameters of COPD. Patients and methods: Seventy patients with stable COPD were enrolled consecutively in this cross-sectional study. Pulmonary function tests, including spirometry, impulse oscillometry (IOS) and the single-breath diffusing capacity of the lungs for carbon monoxide (DLCO), were carried out at rest. Quality of life was assessed by health-related quality of life (HRQoL) questionnaires, including modified Medical Research Council dyspnea scale (mMRC), St George’s Respiratory Questionnaire, Chronic Obstructive Pulmonary Disease Assessment Test (CAT) and Clinical Chronic Obstructive Pulmonary Questionnaire. Both steps and distance were measured in the following 6-minute walk test (6MWT). Results: Both S6MWT and D6MWT showed significant correlation with spirometry, IOS, DLCO parameters and HRQoL questionnaires score. Both pre- and post-6MWT inspiratory capacity showed significant correlation with S6MWT (ρ=0.338, P=0.004; ρ=0.359, P=0.002, respectively), whereas did not correlate with D6MWT (ρ=0.145, P=0.230; ρ=0.160, P=0.189, respectively). In stepwise multiple regression analysis, mMRC grade, age and CAT score remained as significant predictors in the final model for D6MWT (adjusted R2=0.445, P |
| Databáze: | OpenAIRE |
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