MAST CELL SENSITIZING ANTIBODIES IN EXPERIMENTAL CANDIDIASIS
| Autor: | E. Eylan, Nurith Vardinon, E. Segal, Jeanna Schwartz |
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| Rok vydání: | 1974 |
| Předmět: |
Hot Temperature
Time Factors medicine.medical_treatment Guinea Pigs Immunology Antibodies Antigen Candida albicans medicine Homologous chromosome Animals Immunology and Allergy Hypersensitivity Delayed Mast Cells Skin Tests biology business.industry Candidiasis Degranulation biology.organism_classification Mast cell In vitro medicine.anatomical_structure Antibody Formation biology.protein Immunization Antibody business Adjuvant |
| Zdroj: | Allergy. 30:1-8 |
| ISSN: | 1398-9995 0105-4538 |
| Popis: | Inoculation into foot-pads of guinea-pigs of a living suspension of Candida albicans together with Complete Freund's Adjuvant, provoked a hypersensitive state, characterized by: 1) positive skin tests; 2) direct degranulation of peritoneal mast cells when exposed in vitro to the antigen; and 3) homologous "mast cell sensitizing antibodies" detected by the "indirect mast cell degranulation test". The mast cell sensitizing antibodies were heat labile, and their activity could not be restored by complement. |
| Databáze: | OpenAIRE |
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