Layer-specific myocardial function in asymptomatic cats with obstructive hypertrophic cardiomyopathy assessed using 2-dimensional speckle-tracking echocardiography

Autor: Hirotaka Matsumoto, Ryohei Suzuki, Takahiro Teshima, Hidekazu Koyama, Hiroki Yoshimatsu, Ayaka Niina, Yohei Mochizuki
Rok vydání: 2018
Předmět:
Male
medicine.medical_specialty
040301 veterinary sciences
Cardiology
cat
Speckle tracking echocardiography
Standard Article
030204 cardiovascular system & hematology
Cat Diseases
Asymptomatic
epicardial strain
0403 veterinary science
03 medical and health sciences
strain
0302 clinical medicine
Internal medicine
myocardium
medicine
Animals
Circumferential strain
cardiovascular diseases
feline
Retrospective Studies
lcsh:Veterinary medicine
CATS
General Veterinary
business.industry
Significant difference
endocardial strain
Hypertrophic cardiomyopathy
Heart
04 agricultural and veterinary sciences
Cardiomyopathy
Hypertrophic
Myocardial function
medicine.disease
Standard Articles
Echocardiography
Case-Control Studies
Asymptomatic Diseases
Cats
cardiovascular system
lcsh:SF600-1100
Female
SMALL ANIMAL
medicine.symptom
Obstructive hypertrophic cardiomyopathy
business
Zdroj: Journal of Veterinary Internal Medicine, Vol 33, Iss 1, Pp 37-45 (2019)
Journal of Veterinary Internal Medicine
ISSN: 0891-6640
DOI: 10.1111/jvim.15339
Popis: Background Hypertrophic cardiomyopathy (HCM), a primary disorder of the myocardium, is the most common cardiac disease in cats. However, determination of layer-specific myocardial function with 2D speckle-tracking echocardiography in cats with asymptomatic HCM has not yet been reported. Objectives To quantitatively measure layer-specific myocardial function of asymptomatic cats with HCM. Animals Ten client-owned, asymptomatic cats with obstructive HCM and 13 healthy cats. Methods A retrospective, case-control study. Cats underwent assessment of layer-specific myocardial function (whole, endocardial, and epicardial) in the longitudinal and circumferential directions by using 2D speckle-tracking echocardiography. Results Longitudinal strains were significantly lower in cats with HCM than controls in the whole (-15.5% vs -19.1%), endocardial (-18.3% vs -21.8%), and epicardial (-13.1% vs -16.8%) layers. Circumferential strains in whole and epicardial layers also were significantly lower in cats with HCM as compared with controls (-15.0% vs -20.2% and - 4.4% vs -9.4%, respectively). However, no significant difference was found between cats with HCM and controls in the global circumferential strain in the endocardial layer (-31.2% vs -34.2%). The circumferential endocardial-to-epicardial strain ratio was significantly higher in cats with HCM than in controls (6.1 vs 3.5). Conclusions and clinical importance Layer-specific myocardial function assessed by 2D speckle-tracking echocardiography differed in asymptomatic cats with obstructive HCM compared to controls despite their apparently normal systolic function, as determined by conventional echocardiography. The maintained endocardial circumferential strain and higher circumferential endocardial-to-epicardial strain ratio may reflect compensation for occult systolic dysfunction in cats with obstructive HCM.
Databáze: OpenAIRE
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