Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
| Autor: | Soon-Nang Park, Sug-Joon Ahn, Joong-Ki Kook |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
lcsh:QR1-502
Peptidoglycan ursolic acid Microbiology lcsh:Microbiology Streptococcus mutans Terpene chemistry.chemical_compound Ursolic acid oleanolic acid peptidoglycan biosynthesis Microbial Physiology Media Technology Peptidoglycan biosynthesis Oleanolic acid Gene biology Gene Expression Regulation Bacterial Antimicrobial biology.organism_classification Triterpenes Anti-Bacterial Agents Biosynthetic Pathways chemistry Biochemistry Streptococcus mutans UA159 |
| Zdroj: | Brazilian Journal of Microbiology, Vol 46, Iss 2, Pp 613-617 (2015) Brazilian Journal of Microbiology |
| ISSN: | 1678-4405 |
| Popis: | In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans. |
| Databáze: | OpenAIRE |
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