Classic form of hypoplastic left heart syndrome diagnosed post-natally: an autopsy report
| Autor: | Diana Arrais de Souza Rangel, Ana Carolina Neves de Carvalho, Lucas Braga Mota, Heli Samuel Pinto Souza, Cristiane Rúbia Ferreira, Vera Demarchi Aiello, Ana Maria Andrello Gonçalves Pereira de Melo |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
lcsh:Internal medicine
medicine.medical_specialty Heart disease medicine.medical_treatment Shock Cardiogenic lcsh:Medicine Autopsy Prenatal diagnosis Pathology and Forensic Medicine Hypoplastic left heart syndrome Quality of life Hypoplastic Left Heart Syndrome Internal Medicine medicine Stage (cooking) lcsh:RC31-1245 Heart transplantation business.industry lcsh:R Shock Cardiogenic medicine.disease Surgery Article / Autopsy Case Report medicine.anatomical_structure Ventricle Artigo / Relato de Caso de Autópsia Respiratory Insufficiency business AUTÓPSIA |
| Zdroj: | Autopsy & Case Reports Autopsy and Case Reports, Vol 4, Iss 3 (2014) Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 2236-1960 |
| DOI: | 10.4322/acr.2014.025 |
| Popis: | Hypoplastic left heart syndrome (HLHS) is a congenital heart disease, which, despite the current improved knowledge about its management and surgical treatment, is still associated with high mortality, especially in the early neonatal period and before the second stage of reconstruction surgery. The low rate of prenatal diagnosis and delayed diagnostic suspicion results in unsuccessful therapeutic intervention, even though the real impact of early diagnosis and intervention on mortality and quality of life of patients is still uncertain. Fortunately, this syndrome of challenging treatment is not that frequent. It involves a spectrum of obstructions to the blood flow within the left heart and is characterized by an inappropriate size of the left ventricle associated with a wide variety of valvular dysfunctions. Treatment ranges from heart transplantation to palliative surgical procedures. The authors describe a case of a newborn with HLHS, whose diagnosis was made after birth because of early respiratory failure. Despite the use of prostaglandin the newborn died. An autopsy was performed and the anatomical findings were described. |
| Databáze: | OpenAIRE |
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