Fetal cardiac geometry and function in pregnancies with well-controlled gestational diabetes mellitus using Fetal HQ
| Autor: | Qin Chen, Wenjia Lei, Rui Zhang, Yongen Liang, Qiyun Fan, Yunyu Chen, Hongying Wang, Haiyu Wang, Yingheng Wu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Cardiac function curve
Heart Defects Congenital medicine.medical_specialty endocrine system diseases Heart Ventricles Ultrasonography Prenatal Contractility Fetal Heart Pregnancy Internal medicine Medicine Humans Cardiac geometry Fetus business.industry nutritional and metabolic diseases Obstetrics and Gynecology medicine.disease Gestational diabetes Diabetes Gestational Echocardiography Pediatrics Perinatology and Child Health cardiovascular system Cardiology Observational study Female business |
| Zdroj: | The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25) |
| ISSN: | 1476-4954 |
| Popis: | To determine whether abnormal cardiac shape and ventricular global, transverse, and longitudinal contractility are present in fetuses of women with well-controlled GDM. A prospective observational study was performed on 80 fetuses of women with well-controlled GDM and 90 control fetuses. Using Fetal HQ, a new speckle-tracking technique, cardiac shape, global contractility, transverse contractility, and longitudinal contractility were calculated. The number and percentage of fetuses with z score values below 5th or above 95th were computed. Compared with controls, there were no significant differences in the frequency of cardiac geometric abnormalities in GDM fetuses. Despite good glycemic control, 60.0% of fetuses in the well-controlled GDM group had one or more types of global, longitudinal, and transverse contractility abnormalities of one or both ventricles, but more frequent on the right ventricle (RV, 50%). The most frequent abnormality of the RV occurred in the transverse contractility (35%), followed by abnormalities of global contractility (25%), and longitudinal contractility (21.3%), compared with controls. The left ventricle (LV) analysis demonstrated that the percentage of study fetuses with only transverse contractility abnormality (18.8%) was significantly higher. Despite good glycemic control, abnormal ventricular contractility was present in fetuses of women with GDM, but more frequent in the RV. For both the RV and LV, transverse ventricular contractility abnormality were more prevalent than abnormal global and longitudinal contractility. Fetuses of women with GDM should be evaluated for ventricular contractility abnormality and have more follow-ups despite good glycemic control. |
| Databáze: | OpenAIRE |
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