The Importance of Neutrophil/Lymphocyte and Lymphocyte/Monocyte Ratios in The Diagnosis of Influenza in Children
| Autor: | Mesut Okur, Hayrettin Temel, Mehmet Gündüz, Merve Celebi, Ayşe İstanbullu Tosun |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Neutrophils Lymphocyte Lymphocyte / Monocyte Gastroenterology Monocytes General Biochemistry Genetics and Molecular Biology Antigen Internal medicine Influenza Human Humans Medicine In patient Lymphocytes Child Retrospective Studies medicine.diagnostic_test business.industry Neutrophil / Lymphocyte Monocyte Significant difference virus diseases Complete blood count Influenza a Prognosis Influenza Pediatric clinic Blood Cell Count medicine.anatomical_structure business |
| Zdroj: | Clinical Laboratory. 67 |
| ISSN: | 1433-6510 |
| DOI: | 10.7754/clin.lab.2020.200907 |
| Popis: | Background: We aimed to analyze the neutrophil/lymphocyte ratio (NLR) and lymphocyte/monocyte ratio (LMR) to investigate their value in supporting the diagnosis of influenza in cases with influenza-like symptoms. Methods: A total of 5,693 pediatric patients who applied to the Pediatric Clinic between January 2015 and Decem-ber 2018 were included in the study. Complete blood count and influenza rapid antigen tests were evaluated at the time of admission. Results: The mean LMR was significantly lower in patients with influenza A than non-influenza A patients (p < 0.001). LMR was also significantly lower in those with influenza A or B compared to those in the influenza-nega-tive group (p < 0.001). There was no significant difference (p = 0.83) in terms of the mean LMR between influenza B positive and negative patients. The mean NLR was significantly higher in influenza A positive patients in com-parison with influenza A negative patients (p < 0.001), and it was significantly lower in influenza B positive pa-tients than in influenza B negative patients (p < 0.001). Conclusions: We concluded that LMR and NLR, which had been rarely examined in the literature, had important value in the diagnosis of influenza. However, these values alone were far from being sufficient for the definitive di-agnosis of influenza. |
| Databáze: | OpenAIRE |
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