Effects of Chronic and Acute Pulmonary Hyperinflation on Phrenic Nerve Conduction in Patients with COPD
| Autor: | Claudio Tantucci, Bruno Guarneri, Lara Bertolovic, Paolo Bettini, Laura Pini, Simona Marino, Roberto Magri |
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| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Exacerbation Pulmonary hyperinflation Diaphragm Neural Conduction Phrenic nerve conduction macromolecular substances pulmonary hyperinflation 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Internal medicine medicine Reaction Time COPD Humans In patient 030212 general & internal medicine Rest (music) acute exacerbations Phrenic nerve Aged Aged 80 and over business.industry fungi food and beverages Recovery of Function Middle Aged medicine.disease Diaphragm (structural system) diaphragm phrenic nerve Phrenic Nerve 030228 respiratory system Cardiology Disease Progression Respiratory Mechanics Female business Lung Volume Measurements Inspiratory Capacity |
| Zdroj: | COPD. 17(4) |
| ISSN: | 1541-2563 |
| Popis: | In patients with moderate-to-severe Chronic Obstructive Pulmonary Disorder (COPD), pulmonary hyperinflation can occur at rest and increase during episodes of exacerbation. Among other mechanical constraints, changes in position and configuration of the diaphragm are also induced by increased end-expiratory lung volume. Both descent and flattening of diaphragm might damage the phrenic nerves by stretching their fibers. The study aimed to investigate the phrenic nerve conduction in COPD patients in stable conditions and during COPD exacerbation. In a group of 11 COPD patients without relevant comorbidities in stable conditions and subsequently in another group of 10 COPD patients during in-hospital COPD exacerbation and recovery, measurements of functional respiratory parameters and assessment of phrenic nerves motor conduction by bilateral electric stimulation were performed concurrently. Significant increase in phrenic nerves latency ( |
| Databáze: | OpenAIRE |
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