Variables associated with changes in spirometry in patients with obstructive lung diseases
| Autor: | Charles B. Smith, Richard E. Kanner, Attilio D. Renzetti, Carole A. Golden, Melville R. Klauber |
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| Rok vydání: | 1979 |
| Předmět: |
Male
Spirometry medicine.medical_specialty Vital capacity Respiratory Tract Diseases Vital Capacity One Hundred Fifty FEV1/FVC ratio Forced Expiratory Volume Internal medicine medicine Humans Lung Diseases Obstructive Prospective Studies Lung medicine.diagnostic_test business.industry Smoking Age Factors Regression analysis General Medicine Middle Aged respiratory tract diseases Airway Obstruction medicine.anatomical_structure Social Class alpha 1-Antitrypsin Physical therapy Regression Analysis Female Airway business Respiratory tract |
| Zdroj: | The American Journal of Medicine. 67:44-50 |
| ISSN: | 0002-9343 |
| DOI: | 10.1016/0002-9343(79)90072-x |
| Popis: | One hundred fifty subjects were enrolled in a long-term study of obstructive lung diseases; 84 of these were subjected to five or more spirometric studies over a period of two or more years. Stepdown regression analysis was performed to determine the association between many different variables and the annual rates of change in the forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1). The following associations were noted to be significant (p less than 0.03); more favorable rates of change of the FVC and FEV1 were associated with a higher alpha1-antitrypsin level and older age. Less favorable changes were associated with more years of cigarette smoking, more airway reactivity and more frequent lower respiratory tract illnesses. |
| Databáze: | OpenAIRE |
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