Hepatic Hilar Nerve Block for Hepatic Interventions: Anatomy, Technique, and Initial Clinical Experience in Thermal Ablation of Liver Tumors
| Autor: | Kevin S He, Karl Muchantef, David Valenti, Abdulaziz Algharras, Geoffroy Noel, Ali Bessissow, Nicolas Martinez, Rukshan Fernando, David M. Liu, Tatiana Cabrera, Louis-Martin Boucher |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Ablation Techniques
Male Sedation medicine.medical_treatment Hilum (biology) Pilot Projects Fentanyl Cadaver medicine Humans Pain Management Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Ultrasonography Interventional Aged Bupivacaine business.industry Liver Neoplasms Nerve Block Anatomy Middle Aged Ablation Liver Anesthetic Nerve block Female medicine.symptom business medicine.drug |
| Zdroj: | Radiology. 301:223-228 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiol.2021203410 |
| Popis: | Background Image-guided procedures for treatment of liver diseases can be painful and require heavy sedation of the patient. Local-regional nerve blocks improve pain control and reduce oversedation risks, but there are no documented liver-specific nerve blocks. Purpose To develop a safe and technically simple liver-specific nerve block. Materials and Methods Between March 2017 and October 2019, three cadavers were dissected to evaluate the hepatic hilar anatomy. The hepatic hilar nerves were targeted with transhepatic placement of a needle adjacent to the main portal vein, under US guidance, and evaluated with use of an injection of methylene blue. A hepatic nerve block, using similar technique and 0.25% bupivacaine, was offered to patients undergoing liver tumoral ablation. In a prospective pilot study, 12 patients who received the nerve block were compared with a control group regarding complications, safety, pain scores, and intraoperative opioid requirement. Student t tests were used to compare the groups' characteristics, and Mann-Whitney U tests were used for the measured outcomes. Results Cadaver results confirmed that the hepatic nerves coursing in the hepatic hilum can be targeted with US for injection of anesthetic agents, with adequate spread of injected methylene blue around the nerves in the hepatic hilar perivascular space. The 12 participants (mean age ± standard deviation, 66 years ± 13; eight men) who received a hepatic hilar block before liver thermal ablations demonstrated reduced pain compared with a control group of 12 participants (mean age, 63 years ± 15; eight men) who received only intravenous sedation. Participants who received the nerve block had a lower mean visual analog scale score for pain than the control group (3.9 ± 2.4 vs 7.0 ± 2.8, respectively; P = .01) and decreased need for intraprocedural fentanyl (mean dose, 152 μg ± 78.0 vs 235.4 μg ± 58.2, respectively; P = .01). No major complications occurred in the hepatic hilar nerve block group. Conclusion A dedicated hepatic hilar nerve block with 0.25% bupivacaine can be safely performed to provide anesthesia during liver tumoral ablation. © RSNA, 2021. |
| Databáze: | OpenAIRE |
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