Assessing functional status of cardiac lymphatics: From macroscopic imaging to molecular profiling

Autor: Justyna Niderla-Bielińska, Bogdan Ciszek, Ewa Jankowska-Steifer, Anna Ratajska, Ebba Brakenhielm, Iwona Badurek, Elżbieta Czarnowska, Paweł Matryba
Rok vydání: 2021
Předmět:
Zdroj: Trends in Cardiovascular Medicine. 31:333-338
ISSN: 1050-1738
DOI: 10.1016/j.tcm.2020.06.006
Popis: Here we describe various techniques for visualization of the lymphatic vasculature, particularly in the heart. Addressing macro-, microscopic, and molecular levels of lymphatic organization, we give examples of how to explore the roles of specific antigens/markers expressed in lymphatic vessels and their extracellular matrix as structural and functional elements involved in various biological functions of lymphatics. Some obstacles and technical challenges related to lymphatic visualization are also discussed.
Databáze: OpenAIRE