| Autor: |
Charlotte C. Campbell, Samuel Saslaw |
| Rok vydání: |
1950 |
| Předmět: |
|
| Zdroj: |
American Journal of Public Health and the Nations Health. 40:427-435 |
| ISSN: |
0002-9572 |
| DOI: |
10.2105/ajph.40.4.427 |
| Popis: |
THE coincidence ofpulmonary scarring or calcified nodules and histoplasmin skin sensitivity in tuberculin-negative persons was first described in detail by Christie and Peterson ' and Palmer.2 These and subsequent studies 316 have emphasized that lesions which in the past would have been interpreted as tuberculous in origin may be the result of an infection with Histoplasma capsulatum or some other related organism. Widespread surveys correlating the roentgenographic appearance of pulmonary infiltrates with histoplasmin sensitivity, as well as recent descriptions of non-fatal cases'7' 18 have not only stimulated interest in the disease process known as histoplasmosis but have considerably altered the earlier concept that infection with H. capsulatum was rarely encountered and invariably fatal. The increasing cognizance of this alternate concept has resulted in a relatively larger incidence of detected infections. This, in turn, lends support to the postulate that histoplasmin sensitivity may be a direct result of previous infection with H. capsulatum and that a benign form of the disease is prevalent throughout a wide geographical area of the United States. The correctness of such a postulate can be strengthened by detecting a sufficient number of cases in the early acute phase of the disease. Unfortunately, the exact diagnosis of an infection so protean in nature as histo |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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