Sincalide: A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues
Autor: | Harvey A. Ziessman |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Outpatient procedure Gallbladder disease Sincalide 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Gallbladder contraction Humans Radiology Nuclear Medicine and imaging Radionuclide Imaging Intensive care medicine Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Drug Administration Routes Gallbladder Drug administration General Medicine medicine.disease medicine.anatomical_structure Cholescintigraphy business medicine.drug |
Zdroj: | Journal of Nuclear Medicine Technology. 47:210-212 |
ISSN: | 1535-5675 0091-4916 |
DOI: | 10.2967/jnmt.119.226019 |
Popis: | Sincalide (Kinevac) is widely used in conjunction with cholescintigraphy for a variety of clinical indications. Over the years, numerous publications have verified the optimal infusion methodology. Published data and consensus recommendations emphasize that sincalide, 0.02 μg/kg, should be infused over 60 min. Production problems sometimes limit the availability of sincalide. In that case, non-Food and Drug Administration pharmacy-compounded sincalide may serve as an alternative. Fatty meals have also been used. Various illnesses and drugs may inhibit gallbladder contraction. Thus, these drugs should be withheld for 48 h before the study. Sincalide cholescintigraphy is most commonly used to diagnose or exclude chronic acalculous gallbladder disease. The study should preferably be performed as an outpatient procedure. |
Databáze: | OpenAIRE |
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