Evaluation of global function of the heart in scleroderma patients
| Autor: | Refika Hural, Orhan Kucuksahin, Cetin Erol, Sibel Turhan, Huseyin Goksuluk, Aynur Acibuca, Ozgur Ulas Ozcan, Veysel Kutay Vurgun, Demet Menekse Gerede |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Diastole Sensitivity and Specificity Scleroderma Tissue Doppler echocardiography Fibrosis Internal medicine Image Interpretation Computer-Assisted Ventricular Dysfunction Medicine Humans Radiology Nuclear Medicine and imaging Myocardial Performance Index Isovolumetric contraction Scleroderma Systemic business.industry Reproducibility of Results Middle Aged medicine.disease Connective tissue disease Echocardiography Doppler Global function Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Echocardiography (Mount Kisco, N.Y.). 32(6) |
| ISSN: | 1540-8175 |
| Popis: | Objective Scleroderma is a connective tissue disease characterized by diffuse vascular lesions and fibrosis of the skin and major organs including lungs, kidneys, and heart. When cardiac involvement is clinically evident, it is recognized as a poor prognostic factor. The early detection of cardiac involvement in scleroderma would be desirable both for implementation of preventive measures in the early stages of the disease and for optimal treatment. Methods Left (LV) and right (RV) ventricular function were examined in 31 scleroderma patients and 21 healthy controls. Conventional and tissue Doppler echocardiography was used to evaluate systolic and diastolic function. Systolic indices including systolic (S) velocity, isovolumetric acceleration (IVA), ejection time (ET), and isovolumetric contraction time (IVCT) were measured. Early diastolic (E) velocity, late diastolic (A) velocity, E/A and E’/A’ ratios, isovolumetric relaxation time (IVRT), and deceleration time (DT) were the diastolic measurements obtained. Myocardial performance index (Tei index) calculated by 2 different methods was used to assess global ventricular function. Results In our study; mitral S velocity, biventricular ET, E’, E/A, E’/A’, RV IVA, LV IVA, and tricuspid S velocity were significantly lower in scleroderma patients. Mitral DT, IVCT, and biventricular IVRT, were significantly higher in scleroderma patients (P |
| Databáze: | OpenAIRE |
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