Medical and surgical interventions and outcomes for infants with trisomy 18 (T18) or trisomy 13 (T13) at children's hospitals neonatal intensive care units (NICUs)
| Autor: | Jessica T. Fry, Carl H. Coghill, Isabella Zaniletti, Anita R. Shah, Con Yee Ling, Krishna Acharya, Narendra Dereddy, Robert DiGeronimo, Ankur Datta, Julie Weiner, Laura E. Jackson, Nana Matoba, Christine E Bishop, Helen O. Williams, Girija Natarajan, Amy B. Schlegel, Steven R. Leuthner, Monica H. Wojcik, Jamie Seale, Jason Z Niehaus, Sujir Pritha Nayak, Palliative Care, Kevin L. Sullivan |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Trisomy 13 Syndrome MEDLINE Article 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intensive care Intensive Care Units Neonatal medicine Humans 030212 general & internal medicine Child Retrospective Studies Ethics business.industry Intensive treatment Infant Newborn Obstetrics and Gynecology Infant Retrospective cohort study medicine.disease Hospitals Pediatric Aneuploidy Outcomes research Pediatrics Perinatology and Child Health Trisomy business Surgical interventions Trisomy 18 Syndrome |
| Zdroj: | Journal of Perinatology |
| ISSN: | 1476-5543 |
| Popis: | Objectives To examine characteristics and outcomes of T18 and T13 infants receiving intensive surgical and medical treatment compared to those receiving non-intensive treatment in NICUs. Study design Retrospective cohort of infants in the Children’s Hospitals National Consortium (CHNC) from 2010 to 2016 categorized into three groups by treatment received: surgical, intensive medical, or non-intensive. Results Among 467 infants admitted, 62% received intensive medical treatment; 27% received surgical treatment. The most common surgery was a gastrostomy tube. Survival in infants who received surgeries was 51%; intensive medical treatment was 30%, and non-intensive treatment was 72%. Infants receiving surgeries spent more time in the NICU and were more likely to receive oxygen and feeding support at discharge. Conclusions Infants with T13 or T18 at CHNC NICUs represent a select group for whom parents may have desired more intensive treatment. Survival to NICU discharge was possible, and surviving infants had a longer hospital stay and needed more discharge supports. |
| Databáze: | OpenAIRE |
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