Assessing the Risk of Contrast-Induced Nephropathy Using a Finger Stick Analysis in Recalls from Breast Screening

Autor: Marc B. I. Lobbes, Estelle C. Nijssen, Otto Bekers, Joachim E. Wildberger, C. J. L. Y. van Berlo, I. P. L. Houben
Přispěvatelé: MUMC+: DA BV AIOS Radiologie (9), RS: NUTRIM - R3 - Respiratory & Age-related Health, MUMC+: DA CDL (5), RS: NUTRIM - R4 - Gene-environment interaction, MUMC+: DA BV Klinisch Fysicus (9), Beeldvorming, MUMC+: DA BV Medisch Specialisten Radiologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: DA Beeldvorming (5), RS: CARIM - R3.11 - Imaging
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Contrast Media & Molecular Imaging. Wiley Hindawi Partnership
Contrast Media & Molecular Imaging, Vol 2017 (2017)
Contrast Media & Molecular Imaging
ISSN: 1555-4309
Popis: Purpose. To evaluate whether a handheld point-of-care (POC) device is able to predict and discriminate patients at potential risk of contrast-induced nephropathy (CIN) prior to iodine-based contrast media delivery. Methods and Materials. Between December 2014 and June 2016, women undergoing contrast-enhanced spectral mammography (CESM) with an iodine-based contrast agent were asked to have their risk of CIN assessed by a dedicated POC device (StatSensor CREAT) and a risk factor questionnaire based on national guidelines. Prior to contrast injection, a venous blood sample was drawn to compare the results of POC with regular laboratory testing. Results. A total of 351 patients were included; 344 were finally categorized as low risk patients by blood creatinine evaluation. Seven patients had a eGFR below 60 ml/min/1.73 m2, necessitating additional preparation prior to contrast delivery. The POC device failed to categorize six out of seven patients (86%), leading to (at that stage) unwanted contrast administration. Two patients subsequently developed CIN after 2–5 days, which was self-limiting after 30 days. Conclusion. The POC device tested was not able to reliably assess impairment of renal function in our patient cohort undergoing CESM. Consequently, we still consider classic clinical laboratory testing preferable in patients at potential risk for developing CIN.
Databáze: OpenAIRE