Documentation of off-label use of biologics in Rheumatoid Arthritis

Autor: Joachim R. Kalden, Arthur Kavanaugh, Ferrie Breedveld, Joachim Sieper, Philip J. Mease, Roy Fleischman, Josef S. Smolen, Daniel E. Furst
Rok vydání: 2013
Předmět:
Zdroj: Annals of the Rheumatic Diseases. 72:ii35-ii51
ISSN: 1468-2060
0003-4967
DOI: 10.1136/annrheumdis-2013-consensusapp
Popis: The ‘Updated Consensus Statement on Biological Agents for the Treatment of Rheumatic Diseases’ represents the consensus and efforts of a worldwide group of experts regarding the use of biologics in Rheumatoid Arthritis. That document details the use of biologics in registered uses for those drugs. However, the biologic agents are used ‘off label’ in a very large array of other rheumatic diseases. To some degree, those uses are based on animal studies and mechanistic rationale but they often …
Databáze: OpenAIRE