In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography
| Autor: | Manish D. Kulkarni, Ashley J. Welch, Joseph A. Izatt, Jennifer K. Barton, Siavash Yazdanfar |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Materials science
genetic structures medicine.diagnostic_test business.industry Blood flow Laser Doppler velocimetry eye diseases Atomic and Molecular Physics and Optics Interferometry Optics Optical coherence tomography medicine sense organs Optical Doppler Tomography business Biological imaging Image resolution Preclinical imaging |
| Zdroj: | Optics letters. 22(18) |
| ISSN: | 0146-9592 |
| Popis: | We describe a novel optical system for bidirectional color Doppler imaging of flow in biological tissues with micrometer-scale resolution and demonstrate its use for in vivo imaging of blood flow in an animal model. Our technique, color Doppler optical coherence tomography (CDOCT), performs spatially localized optical Doppler velocimetry by use of scanning low-coherence interferometry. CDOCT is an extension of optical coherence tomography (OCT), employing coherent signal-acquisition electronics and joint time-frequency analysis algorithms to perform flow imaging simultaneous with conventional OCT imaging. Cross-sectional maps of blood flow velocity with |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|