The seroprevalence of the hepatitis B virus in Italian medical students after 3 decades since the introduction of universal vaccination
| Autor: | Antonella Pietronigro, Pietro Sartorelli, Laura Bianciardi, Gabriele Messina, Rosalia Miceli, Federico Occhialini, Chiara Salini |
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| Rok vydání: | 2022 |
| Předmět: |
Adult
Male Hepatitis B virus Students Medical Population medicine.disease_cause Young Adult Seroepidemiologic Studies Medical medicine Humans Seroprevalence Hepatitis B Vaccines Students education Hepatitis B Hepatitis B antibodies Immunization Medical students Seroepidemiological studies Vaccination Cross-Sectional Studies Female Hepatitis B Antibodies Hepatitis B Surface Antigens Infant Newborn Italy education.field_of_study business.industry Public Health Environmental and Occupational Health Infant General Medicine Odds ratio Newborn medicine.disease Confidence interval business Demography |
| Zdroj: | International Journal of Occupational Medicine and Environmental Health. 35:75-80 |
| ISSN: | 1896-494X 1232-1087 |
| Popis: | OBJECTIVES Since 1991 hepatitis B vaccination has been mandatory for all newborns in Italy. The aim of the study was to verify the long-term seroprevalence and the efficacy of hepatitis B vaccination in medical students of the University of Siena. MATERIAL AND METHODS A cross-sectional observational study was conducted on a population of 850 medical students of the University of Siena (322 males and 528 females, mean age: 23 years) by obtaining from the medical reports the serological analysis data for the total anti-hepatitis B antibodies (HBsAb) and information on hepatitis B vaccination (number of vaccine doses, age at the first vaccination, time since the final vaccination dose, country of origin). Raw odds ratios (ORs) and 95% confidence intervals (CIs) were initially calculated to evaluate the association between 2 variables. The adjusted ORs were then calculated using a multivariate logistic regression model to study the association between the variables and the possible confounding factors. RESULTS Overall, 593 students (69.76%) were immunized against hepatitis B, while 257 (30.24%) had HBsAb antibody titer |
| Databáze: | OpenAIRE |
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