Human comparative experimental study of surgical treatment of atrial fibrillation by epicardial techniques
| Autor: | Oussama Al Habash, Antoine Mugniot, Olivier Baron, Jean-Christian Roussel, Thomas Senage, Claire Toquet, Jean-Marc El Arid |
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| Jazyk: | angličtina |
| Předmět: |
Male
Cryoablation Pulmonary and Respiratory Medicine medicine.medical_specialty medicine.medical_treatment Cryotherapy Cryosurgery Heart Conduction System Internal medicine Atrial Fibrillation Ultrasound Cadaver medicine Humans Ultrasound energy Aged Aged 80 and over Arrhythmia surgery business.industry Atrial fibrillation General Medicine medicine.disease Ablation Cardiac surgery Pulmonary Veins Radiofrequency Catheter Ablation Cardiology Female Surgery Experimental surgery Energy source Nuclear medicine business Cardiology and Cardiovascular Medicine Pericardium Research Article |
| Zdroj: | Journal of Cardiothoracic Surgery |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/1749-8090-8-140 |
| Popis: | Background To set up an experimental model of cadaveric heart in order to evaluate and compare histologic transmurality of lesions immediately caused by different energy sources of anti-arrhythmic epicardial devices. Methods Procedures were performed on a cadaveric human heart in orthotopic position with an ischemic time of 48 h at 37° and supported through the use of cardiopulmonary bypass. Three anti-arrhythmic epicardial devices were studied: the bipolar forceps Cardioblate BP (Medtronic) for the radiofrequency, the Epicor Ultracinch LP Ablation device (St. Jude) for ultrasound and the Cardioblate CryoFlex (Medtronic) device for cryoablation. Histological features of lesions made at the pulmonary venous confluence assessed the effectiveness of different energy sources. Results Over 45 experimentations performed, only 28 were considered correct and retained for histological analysis. Three distinct groups were studied according to the type of procedure performed: group 1 (Radiofrequency, n = 12), group 2 (ultrasound, n = 4), group 3 (cryoablation, n = 10) and controls (n = 2). All analysed samples showed histological changes with a success rates of transmurality of 33% for radiofrequency, 25% for ultrasound and 90% for cryotherapy (p |
| Databáze: | OpenAIRE |
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