Plasmid R16 ArdA Protein Preferentially Targets Restriction Activity of the Type I Restriction-Modification System Eco KI
| Autor: | Brian M. Wilkins, Angela T. Thomas, William J. Brammar |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Escherichia coli Proteins
biology Bacterial conjugation Bacteriophages Transposons and Plasmids Repressor DNA Restriction Enzymes biology.organism_classification medicine.disease_cause Bacteriophage lambda Microbiology Molecular biology DNA-binding protein DNA-Binding Proteins Repressor Proteins Plasmid Bacterial Proteins Escherichia coli medicine Restriction modification system Molecular Biology Bacteria Plasmids |
| Zdroj: | Journal of Bacteriology. 185:2022-2025 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.185.6.2022-2025.2003 |
| Popis: | The ArdA antirestriction protein of the IncB plasmid R16 selectively inhibited the restriction activity of Eco KI, leaving significant levels of modification activity under conditions in which restriction was almost completely prevented. The results are consistent with the hypothesis that ArdA functions in bacterial conjugation to allow an unmodified plasmid to evade restriction in the recipient bacterium and yet acquire cognate modification. |
| Databáze: | OpenAIRE |
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