Clinical outcomes of endoscopic submucosal dissection for early gastric cancer in patients with chronic kidney disease

Autor: Shigeto Yoshida, Makoto Higashiyama, Yoji Sanomura, Shinji Tanaka, Koji Arihiro, Shiro Oka, Norifumi Numata, Kazuaki Chayama
Rok vydání: 2013
Předmět:
Zdroj: Journal of Gastroenterology and Hepatology. 28:1632-1637
ISSN: 1440-1746
0815-9319
Popis: Background and Aim Endoscopic submucosal dissection (ESD) is a widely accepted treatment for early gastric cancer (EGC), and the number of ESD performed for EGC in patients with chronic kidney disease (CKD) is increasing. Although patients undergoing hemodialysis tend to bleed and are at high risk for cardiovascular disease, the effectiveness and safety of ESD for EGC in patients with CKD in particular have not been established. The aim of this study was to evaluate the effectiveness and potential adverse effects of ESD for EGC in patients with CKD undergoing hemodialysis. Methods Sixty-three consecutive CKD patients in whom 79 EGCs were treated by ESD between October 2004 and January 2012; 15 of the 63 patients were hemodialysis patients. Complete en bloc resection rate and ESD-related complications in hemodialysis patients versus non-hemodialysis patients were evaluated. Results The complete en bloc resection rate was 100% (15/15) in the hemodialysis patients and 87.5% (56/64) in the non-hemodialysis patients, respectively. The post-ESD bleeding rate was 33% (5/15) and 9% (6/64), respectively (P
Databáze: OpenAIRE