Dually Stabilized Triblock Copolymer Micelles with Hydrophilic Shell and Hydrophobic Interlayer for Systemic Antisense Oligonucleotide Delivery to Solid Tumor
| Autor: | Hyun Jin Kim, Kazuko Toh, Mitsuru Naito, Ick Chan Kwon, Beob Soo Kim, Shigehito Osawa, Hyun Su Min, Yu Yi, Kanjiro Miyata, Kazunori Kataoka, Kotaro Hayashi |
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| Rok vydání: | 2019 |
| Předmět: |
Polymeric micelles
Chemistry 0206 medical engineering Biomedical Engineering Shell (structure) 02 engineering and technology 021001 nanoscience & nanotechnology 020601 biomedical engineering Combinatorial chemistry Micelle Biomaterials Antisense oligonucleotides Copolymer 0210 nano-technology Solid tumor |
| Zdroj: | ACS Biomaterials Science & Engineering. 5:5770-5780 |
| ISSN: | 2373-9878 |
| DOI: | 10.1021/acsbiomaterials.9b00384 |
| Popis: | For intravenous delivery of antisense oligonucleotides (ASOs) to solid tumors, a triblock copolymer was synthesized from poly(2-ethyl-2-oxazoline) (PEtOx), poly(2-n-propyl-2-oxazoline) (PnPrOx), an... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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