Hereditary angioedema, emergency management of attacks by a call center

Autor: Alain Sobel, Gisèle Kanny, Michel Desmaizières, Aiham Ghazali, David Launay, Frédéric Adnet, Tomislav Petrovic, Ludovic Martin, Eric Vicaut, Anne Gompel, Bernard Floccard, Adrien Altar, Paul-Georges Reuter, Olivier Fain, Laurence Bouillet, Frédéric Lapostolle, Isabelle Durand-Zaleski, Nicolas Javaud, Isabelle Boccon-Gibod
Přispěvatelé: Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Université Sorbonne Paris Nord, Centre de référence des angiœdèmes à kinines (CREAK), CHU Grenoble-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université d'Angers (UA), Centre de Référence sur les angiœdèmes à kinines (CREAK), Service de Médecine Interne, Immunologie Clinique et Allergologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Hôpital Louis Mourier - AP-HP [Colombes], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Pierre et Marie Curie - Paris 6 (UPMC), SAMU 93 [Bobigny], Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AP-HP - Hôpital Bichat - Claude Bernard [Paris], URCEco, Hôpital Hôtel-Dieu [Paris], Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CHU Grenoble, Hôpital Lariboisière-Fernand-Widal [APHP], Hôpital Claude Huriez [Lille], CHU Lille, Université de Lille, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL), Hopital port Royal, Partenaires INRAE, Université Paris Descartes - Paris 5 (UPD5), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Internal Medicine
European Journal of Internal Medicine, Elsevier, 2019, 67, pp.42-46. ⟨10.1016/j.ejim.2019.05.007⟩
European Journal of Internal Medicine, 2019, 67, pp.42-46. ⟨10.1016/j.ejim.2019.05.007⟩
ISSN: 0953-6205
1879-0828
DOI: 10.1016/j.ejim.2019.05.007⟩
Popis: International audience; Objective: Hereditary angiœdema (HAE) is a rare autosomal dominant disease characterized by recurrent, unpredictable, potentially life-threatening swelling. Objective is to assess the management of the acute HAE attacks in the real life setting through a call center in France.Methods: A pre-specified ancillary study of SOS-HAE, a cluster-randomized prospective multicenter trial, was conducted. HAE patients were recruited from 8 participating reference centers. The outcome of interest was the rate of hospitalization.Results: onerhundred patients were included. The median (quartile) age was 38 (29-53) years, and 66 (66%) were female. Eighty (80%) patients had HAE type I, 8 (8%) had HAE type II and 12 (12%) patients had FXII-HAE. Fifty-one (51%) patients had experienced at least one time the call center during the follow-up. Nine over 166 (5%) attacks for 9 different patients resulted in hospital admission to the hospital (in the short-stay unit, ie
Databáze: OpenAIRE
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