Fulminant hepatic failure in a patient testing re-positive for SARS-CoV-2: a case report
| Autor: | Aldossary, Bader, Hassan, Ali, Moussa, Mohamed, Alsaif, Hind S., Alfaraj, Dunya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Resuscitation Case Report Re-positive test 030204 cardiovascular system & hematology Re-infection Gastroenterology 03 medical and health sciences 0302 clinical medicine Fulminant hepatic failure Internal medicine medicine 030212 general & internal medicine Case reports business.industry RC86-88.9 Liver failure COVID-19 Medical emergencies. Critical care. Intensive care. First aid medicine.disease medicine.anatomical_structure Abdominal examination Emergency Medicine Vomiting Abdomen Elevated transaminases Liver function medicine.symptom business Viral hepatitis |
| Zdroj: | International Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-5 (2021) International Journal of Emergency Medicine |
| ISSN: | 1865-1380 1865-1372 |
| Popis: | Background Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may not elicit lifelong protective immunity and reinfection could occur. Liver function impairment is a common manifestation of coronavirus disease 2019 (COVID-19). However, acute hepatic failure in the setting of COVID-19 is very rare. Case presentation We report the case of a 47-year-old woman who presented with acute abdominal pain and vomiting. Abdominal examination revealed a soft and lax abdomen with mild tenderness in the right upper quadrant. The patient recovered from COVID-19 2 months previously with negative results on reverse transcription-polymerase chain reaction (RT-PCR). Laboratory investigations revealed markedly elevated transaminases with normal results on viral hepatitis serology panel and undetectable blood paracetamol level. Prior to admission, the patient underwent RT-PCR for SARS-CoV-2, which revealed a positive result. The patient experienced rapid deterioration in the neurological status with a remarkable increase in the liver enzyme levels. Despite aggressive resuscitation, the patient suffered irreversible cardiac arrest and died. Conclusion Fulminant hepatic failure is a rare manifestation in patients with re-positive RT-PCR tests for SARS-CoV-2. Clinicians should maintain a high index of suspicion for hepatic injury with active monitoring of liver enzymes. |
| Databáze: | OpenAIRE |
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