Periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis
| Autor: | Recep Dursun, Sema S. Hakki, Abdullah Seckin Ertugrul, Uğur Arslan |
|---|---|
| Přispěvatelé: | Selçuk Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Male
oral lichen plan US Gastroenterology Aggregatibacter actinomycetemcomitans Prevotella intermedia Gingivitis 0302 clinical medicine Actinobacillus Infections Bacteroidaceae Infections Tannerella forsythia Bacteroides 0303 health sciences biology Dental Plaque Index Treponema denticola Middle Aged Bacteroides Infections 3. Good health Original Article Female medicine.symptom Periodontal Index Porphyromonas gingivalis Adult medicine.medical_specialty Dental Plaque Microbiology 03 medical and health sciences oral lichen planus stomatognathic system Internal medicine Gram-Negative Bacteria Periodontal Attachment Loss medicine Humans Periodontal Pocket General Dentistry 030304 developmental biology Periodontitis Treponemal Infections business.industry 030206 dentistry medicine.disease biology.organism_classification Chronic periodontitis stomatognathic diseases Chronic Periodontitis Oral lichen planus business Lichen Planus Oral |
| Zdroj: | International Journal of Oral Science |
| ISSN: | 2049-3169 1674-2818 |
| Popis: | WOS: 000321532600006 PubMed: 23743616 Oral lichen planus (OLP) is a chronic inflammatory disease that is frequently detected in oral tissues. The aim of our study was to identify the prevalence of the detection of periodontopathogenic microorganisms (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola in OLP patients and to compare with this prevalence of periodontopathogenic microorganisms in healthy non-OLP patients. Our study included 27 (18 chronic periodontitis (OLPP) and 9 gingivitis (OLPG)) patients diagnosed with OLP along with 26 (13 chronic periodontitis (HP) and 13 gingivitis (HG)) healthy non-OLP patients. The multiplex polymerase chain reaction (PCR) with subsequent reverse hybridization method (micro-I Dent) was used for identifying periodontopathogenic microorganisms present in subgingival plaque samples. The percentages of detection for A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola in subgingival plaque samples taken from OLP patients (OLPG and OLPP) were 18.5%, 85.1%, 81.4%, 88.8% and 74%, respectively. Meanwhile, in the non-OLP patients (HG and HP), these values were 7.6%, 50%, 46.1%, 73% and 57.7%, respectively. Thus, comparing the non-OLP groups with the OLP groups, the periodontopathogens' percentages of detection in the OLP groups were higher than those in the non-OLP groups. According to our study results, OLP patients have higher levels of infection with A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola than non-OLP patients. We argue that the high percentages in patients with OLP may help identify the importance of periodontopathogenic microorganisms in the progress of periodontal diseases of OLP. Turkey Scientific and Technological Research CouncilTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [106S340]; Selcuk University Coordination of Scientific ResearchSelcuk University [06202034]; Open Fund of State Key Laboratory of Oral Diseases, Sichuan University This study has been performed with project support from the Turkey Scientific and Technological Research Council (project no. 106S340) and Selcuk University Coordination of Scientific Research (project no. 06202034). Publication of this manuscript is supported by Open Fund of State Key Laboratory of Oral Diseases, Sichuan University. |
| Databáze: | OpenAIRE |
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